Magnetically Responsive Negative Acoustic Contrast Microparticles for Bioanalytical Applications.

TitleMagnetically Responsive Negative Acoustic Contrast Microparticles for Bioanalytical Applications.
Publication TypeJournal Article
Year of Publication2016
AuthorsKA Ohiri, BA Evans, CW Shields, RA Gutiérrez, NJ Carroll, BB Yellen, and GP López
JournalAcs Applied Materials & Interfaces
Volume8
Issue38
Start Page25030
Pagination25030 - 25035
Date Published09/2016
Abstract

Smart colloidal particles are routinely used as carriers for biological molecules, fluorescent reporters, cells, and other analytes for the purposes of sample preparation and detection. However, such particles are typically engineered to respond to a single type of stimulus (e.g., commercial magnetic beads to magnetic fields). Here, we demonstrate a unique class of particles that display both positive magnetic contrast and negative acoustic contrast in water. This dual functionality allows for fine spatiotemporal control, enabling multiple separation modalities and increasing the utility of the particles in various chemical and biological assays.

DOI10.1021/acsami.6b09591
Short TitleAcs Applied Materials & Interfaces